Starting treatment for prostate cancer is a significant step — one that often comes with a mix of hope, concern, and questions. If your doctor has prescribed Enzalutamide 160 mg for you or a loved one, it's natural to want to understand what lies ahead.
This blog is your comprehensive guide to what you can expect when beginning treatment with enzalutamide capsules, including how the medication works, possible side effects, lifestyle considerations, and even information about the enzalutamide price and financial support. Let’s walk through it all, step by step.
What is Enzalutamide 160 mg?
Enzalutamide is a type of androgen receptor inhibitor — a class of medications designed to block the effects of male hormones (androgens) like testosterone, which can fuel the growth of prostate cancer cells. It is commonly used to treat:
Metastatic castration-resistant prostate cancer (mCRPC)
Non-metastatic castration-resistant prostate cancer
Metastatic hormone-sensitive prostate cancer (mHSPC)
The standard dosage is Enzalutamide 160 mg, usually taken as four 40 mg capsules once daily, either with or without food.
How Do Enzalutamide Capsules Work?
Testosterone can encourage prostate cancer cells to grow. Enzalutamide works by blocking the androgen receptors, preventing testosterone from binding to them. This disrupts the cancer's ability to thrive, which can slow down or even stop its progression.
Unlike some other treatments, enzalutamide tablets 160 mg do not require injections or hospital visits for administration — you simply take them at home daily, making it a convenient option for many patients.
Starting Treatment: What to Expect
- Taking Your First Dose
You'll begin by taking enzalutamide capsules at a dose of 160 mg per day. That’s four 40 mg capsules all at once. Be sure to:
- Take the capsules at the same time every day
- Swallow them whole — don’t chew, crush, or break them
- Stay consistent, even on weekends and holidays
- Set reminders on your phone or use a pill organizer to help you stay on track.
- Monitoring and Doctor Visits
- Once treatment begins, your doctor will regularly monitor:
- PSA levels to evaluate treatment effectiveness
- Blood pressure, as high blood pressure is a known side effect
- Liver function and blood counts
- Imaging scans to assess tumor activity
- Regular check-ins help catch side effects early and allow your doctor to adjust your treatment plan if needed.
Common Side Effects of Enzalutamide
Like most cancer medications, enzalutamide tablets 160 mg can cause side effects. Some of the most common include:
Fatigue
Up to 50% of patients report fatigue. This may feel like a deep, persistent tiredness. Light exercise, such as walking or yoga, can actually help improve energy levels.
Hot Flashes
Hot flashes and sweating are common due to hormonal changes. Dressing in layers and staying hydrated can help ease these symptoms.
High Blood Pressure
Enzalutamide may cause or worsen hypertension. Your doctor may prescribe medication or recommend lifestyle changes to manage it.
Mood Changes
Some men report depression, irritability, or anxiety. These symptoms are manageable, especially if identified early. Don’t hesitate to ask for support.
Rare: Seizures
A very small percentage of patients may experience seizures. This is rare but serious. Inform your doctor if you have a history of seizures, brain injury, or stroke.
Gynecomastia (Breast Tenderness)
Hormonal changes may cause mild breast swelling or tenderness. This can be managed with medication or, in some cases, radiation therapy.
Falls and Bone Health
There may be an increased risk of falls or fractures. Calcium and vitamin D supplements, along with regular weight-bearing exercises, can strengthen bones.
How Long Will You Take Enzalutamide?
Enzalutamide 160 mg is often taken for an extended period — typically until the medication stops working or side effects become unmanageable. Some men take it for several months or even years, depending on how the cancer responds.
Your doctor may adjust your dosage or switch to a different treatment based on ongoing lab results and how you feel.
Lifestyle Tips During Enzalutamide Treatment
Taking care of your body and mind during treatment can enhance your quality of life and make the process easier to manage.
Nutrition
Focus on whole, anti-inflammatory foods: leafy greens, berries, whole grains, lean proteins, and healthy fats
Avoid excessive sugar, alcohol, and processed foods
Consider seeing a dietitian who specializes in oncology nutrition
Exercise
Light exercise like walking or swimming can reduce fatigue
Strength training helps maintain muscle and bone strength
Exercise also supports mood and cardiovascular health
Mental Health
Prostate cancer treatment can affect self-image, libido, and emotions
Don’t hesitate to seek support from a counsellor or join a prostate cancer support group
Meditation, breathing exercises, and journaling may help with stress
Cost and Insurance: Understanding Enzalutamide 160 mg Price
One of the most common concerns patients have is about the enzalutamide 160 mg price. Unfortunately, branded versions of the medication, such as Xtandi®, can be costly — sometimes several thousand dollars per month.
Is There a Generic Version?
Yes, enzalutamide generic price options have become more accessible in recent years. Generic versions typically offer the same medical benefits at a significantly lower cost, making treatment more affordable for many patients.
Always ask your doctor or pharmacist if a generic enzalutamide is available and whether your insurance covers it.
Financial Assistance Options
If you’re worried about cost, here are a few options that might help:
- Manufacturer assistance programs (e.g., Astellas Support Solutions)
- Nonprofits like the Patient Access Network (PAN) Foundation or CancerCare
- Pharmacy savings cards
- Medicare and supplemental plans
- Speak with your care team’s financial counselor — they often have resources and contacts to help reduce out-of-pocket expenses.
When to Call Your Doctor
Call your healthcare provider if you notice:
- Signs of a seizure or loss of consciousness
- Sudden mood changes, confusion, or depression
- Severe fatigue or dizziness
- Fever or signs of infection
- New or worsening chest pain
- Unusual bleeding or bruising
- Loss of appetite or rapid weight loss
It’s better to over-communicate with your care team than to wait and risk complications.
A Word About Long-Term Outlook
Enzalutamide 160 mg capsules are not a cure for prostate cancer, but they can slow disease progression, reduce symptoms, and extend survival in many men. When used alongside other treatments like hormone therapy, radiation, or chemotherapy, it can play a powerful role in your overall treatment plan.
The most successful treatment journeys are those where patients are:
- Well-informed
- Engaged with their healthcare team
- Proactive about side effects and quality of life
Final Thoughts: Moving Forward with Confidence
Beginning treatment with enzalutamide capsules 160 mg can feel overwhelming at first, but knowledge is power. Now that you know what to expect — from side effects to costs — you’re in a better position to take control of your health journey.
Stay in close contact with your medical team, follow your treatment plan consistently, and don’t be afraid to ask for help — physically, emotionally, or financially.
